Alcohol interactions
Overview
Alcohol (beer, wine, liquor) is alcohol (ethanol) in drinks. In our database it has 64 known interactions with common medicines and substances: 13 serious, 49 that need caution and 2 minor.
Avoid / serious 13 interactions
Alcohol greatly increases sedationBuprenorphine-naloxone
Alcohol and opioids can stop your breathingClonazepam
Alcohol greatly increases sedationCodeine
Alcohol and opioids can stop your breathingDiazepam
Alcohol greatly increases sedationHydrocodone
Alcohol and opioids can stop your breathingKratom
Alcohol and opioids can stop your breathingLorazepam
Alcohol greatly increases sedationMetronidazole
Avoid alcohol during treatment and for 3 days afterMorphine
Alcohol and opioids can stop your breathingOxycodone
Alcohol and opioids can stop your breathingTramadol
Alcohol and opioids can stop your breathingZolpidem
Alcohol greatly increases sedation
Use caution 49 interactions
Liver damage risk with heavy drinkingAmitriptyline
Combined drowsinessAmphetamine salts
Alcohol and ADHD stimulants strain the heartAripiprazole
Alcohol adds to drowsiness and dizzinessAspirin
Stomach bleeding riskBaclofen
Alcohol adds to drowsiness and dizzinessBupropion
Alcohol and seizure riskCannabis
Combined drowsinessCelecoxib
Stomach bleeding riskCitalopram
Alcohol can worsen side effects and moodClonidine
Combined drowsinessCyclobenzaprine
Alcohol adds to drowsiness and dizzinessDayQuil
Liver damage risk with heavy drinkingDiclofenac
Stomach bleeding riskDiphenhydramine
Alcohol adds to drowsiness and dizzinessDoxylamine
Alcohol adds to drowsiness and dizzinessDuloxetine
Alcohol can worsen side effects and moodEmpagliflozin
Low blood sugar and other risksEscitalopram
Alcohol can worsen side effects and moodExcedrin
Stomach bleeding riskFluoxetine
Alcohol can worsen side effects and moodGabapentin
Alcohol adds to drowsiness and dizzinessGlipizide
Low blood sugar and other risksHydroxyzine
Alcohol adds to drowsiness and dizzinessIbuprofen
Stomach bleeding riskInsulin
Low blood sugar and other risksLamotrigine
Alcohol can worsen side effects and moodLevetiracetam
Combined drowsinessLisdexamfetamine
Alcohol and ADHD stimulants strain the heartMeclizine
Alcohol adds to drowsiness and dizzinessMeloxicam
Stomach bleeding riskMetformin
Low blood sugar and other risksMethocarbamol
Alcohol adds to drowsiness and dizzinessMethylphenidate
Alcohol and ADHD stimulants strain the heartMirtazapine
Combined drowsinessNaproxen
Stomach bleeding riskNyQuil
Alcohol adds to drowsiness and dizzinessParoxetine
Alcohol can worsen side effects and moodPhentermine
Alcohol and ADHD stimulants strain the heartPregabalin
Alcohol adds to drowsiness and dizzinessPromethazine
Alcohol adds to drowsiness and dizzinessQuetiapine
Alcohol adds to drowsiness and dizzinessSertraline
Alcohol can worsen side effects and moodSildenafil
Heavy drinking can drop blood pressureTadalafil
Heavy drinking can drop blood pressureTizanidine
Alcohol adds to drowsiness and dizzinessTopiramate
Alcohol can worsen side effects and moodTrazodone
Combined drowsinessVenlafaxine
Alcohol can worsen side effects and mood
Minor 2 interactions
In-depth guides
No known interaction found
Our rules found no interaction between Alcohol and: Acyclovir, Albuterol, Allopurinol, Amlodipine, Amoxicillin, Amoxicillin-clavulanate, Apixaban, Atenolol, Atorvastatin, Azithromycin, Birth control pills, Bismuth subsalicylate, Buspirone, Caffeine, Calcium carbonate, Carvedilol, Cephalexin, Cetirizine, Ciprofloxacin, Clindamycin, Clopidogrel, Colchicine, Creatine, Dextromethorphan, Digoxin, Doxycycline, Esomeprazole, Estradiol, Famotidine, Fexofenadine, Finasteride, Fish oil, Fluconazole, Furosemide, Grapefruit juice, Guaifenesin, Hydrochlorothiazide, Hydroxychloroquine, Iron supplements, Isotretinoin, Levofloxacin, Levothyroxine, Lisinopril, Lithium, Loperamide, Loratadine, Losartan, Magnesium, Methotrexate, Methylprednisolone, Metoprolol, Montelukast, Naltrexone, Nicotine, Nitrofurantoin, Omeprazole, Ondansetron, Oseltamivir, Pantoprazole, Paxlovid, Phenylephrine, Potassium supplements, Pravastatin, Prednisone, Probiotics, Propranolol, Pseudoephedrine, Rivaroxaban, Rosuvastatin, Semaglutide, Simvastatin, Spironolactone, St. John's wort, Sulfamethoxazole-trimethoprim, Sumatriptan, Tamsulosin, Tirzepatide, Turmeric, Valacyclovir, Vitamin D, Warfarin, Zinc.
Add at least two medicines, supplements or alcohol.
Sources
There is no single FDA label for this item, so interactions listed here come from the FDA labels of the medicines it interacts with, and from NIH guidance where noted.
This list covers the 147 medicines and substances in our database. It is not a complete list of every possible interaction. Always tell your doctor and pharmacist about every medicine, supplement and herbal product you take.