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Tamsulosin interactions

Updated October 4, 2026How we check

Overview

Tamsulosin (Flomax) is an alpha blocker for enlarged prostate. In our database it has 17 known interactions with common medicines and substances: 0 serious, 5 that need caution and 12 minor.

Use caution 5 interactions

Minor 12 interactions

No known interaction found

Our rules found no interaction between Tamsulosin and: Acetaminophen, Acyclovir, Albuterol, Alcohol, Allopurinol, Alprazolam, Amitriptyline, Amoxicillin, Amoxicillin-clavulanate, Amphetamine salts, Apixaban, Aripiprazole, Ashwagandha, Aspirin, Atorvastatin, Azithromycin, Baclofen, Birth control pills, Bismuth subsalicylate, Buprenorphine-naloxone, Bupropion, Buspirone, Caffeine, Calcium carbonate, Cannabis, Celecoxib, Cephalexin, Cetirizine, Ciprofloxacin, Citalopram, Clindamycin, Clonazepam, Clopidogrel, Codeine, Colchicine, Creatine, Cyclobenzaprine, Dextromethorphan, Diazepam, Diclofenac, Digoxin, Diphenhydramine, Doxycycline, Doxylamine, Duloxetine, Empagliflozin, Escitalopram, Esomeprazole, Estradiol, Excedrin, Famotidine, Fexofenadine, Finasteride, Fish oil, Fluconazole, Fluoxetine, Gabapentin, Glipizide, Grapefruit juice, Guaifenesin, Hydrocodone, Hydroxychloroquine, Hydroxyzine, Ibuprofen, Insulin, Iron supplements, Isotretinoin, Kratom, Lamotrigine, Levetiracetam, Levofloxacin, Levothyroxine, Lisdexamfetamine, Lithium, Loperamide, Loratadine, Lorazepam, Magnesium, Meclizine, Melatonin, Meloxicam, Metformin, Methocarbamol, Methotrexate, Methylphenidate, Methylprednisolone, Metronidazole, Mirtazapine, Montelukast, Morphine, Naltrexone, Naproxen, Nicotine, Nitrofurantoin, NyQuil, Omeprazole, Ondansetron, Oseltamivir, Oxycodone, Pantoprazole, Paroxetine, Paxlovid, Phentermine, Potassium supplements, Pravastatin, Prednisone, Pregabalin, Probiotics, Promethazine, Quetiapine, Rivaroxaban, Rosuvastatin, Semaglutide, Sertraline, Simvastatin, St. John's wort, Sulfamethoxazole-trimethoprim, Sumatriptan, Tirzepatide, Topiramate, Tramadol, Trazodone, Turmeric, Valacyclovir, Venlafaxine, Vitamin D, Warfarin, Zinc, Zolpidem.

Add at least two medicines, supplements or alcohol.

Sources

Source: FDA label for Tamsulosin on DailyMed (effective 2026-08), plus the labels of each interacting medicine.

This list covers the 147 medicines and substances in our database. It is not a complete list of every possible interaction. Always tell your doctor and pharmacist about every medicine, supplement and herbal product you take.