Amphetamine salts interactions
Overview
Amphetamine salts (Adderall) is a stimulant ADHD medicine. In our database it has 29 known interactions with common medicines and substances: 0 serious, 27 that need caution and 2 minor.
Use caution 27 interactions
Alcohol and ADHD stimulants strain the heartAmitriptyline
Serotonin syndrome riskBupropion
Higher seizure riskBuspirone
Serotonin syndrome riskCitalopram
Serotonin syndrome riskCyclobenzaprine
Serotonin syndrome riskDayQuil
Serotonin syndrome riskDextromethorphan
Serotonin syndrome riskDuloxetine
Serotonin syndrome riskEscitalopram
Serotonin syndrome riskFluoxetine
Serotonin syndrome riskLisdexamfetamine
Two stimulants at onceLithium
Serotonin syndrome riskMethylphenidate
Two stimulants at onceMirtazapine
Serotonin syndrome riskNyQuil
Serotonin syndrome riskOndansetron
Serotonin syndrome riskParoxetine
Serotonin syndrome riskPhentermine
Two stimulants at oncePhenylephrine
Can raise blood pressure and heart ratePseudoephedrine
Can raise blood pressure and heart rateSertraline
Serotonin syndrome riskSt. John's wort
Serotonin syndrome riskSumatriptan
Serotonin syndrome riskTramadol
Serotonin syndrome riskTrazodone
Serotonin syndrome riskVenlafaxine
Serotonin syndrome risk
Minor 2 interactions
In-depth guides
No known interaction found
Our rules found no interaction between Amphetamine salts and: Acetaminophen, Acyclovir, Albuterol, Allopurinol, Alprazolam, Amlodipine, Amoxicillin, Amoxicillin-clavulanate, Apixaban, Aripiprazole, Ashwagandha, Aspirin, Atenolol, Atorvastatin, Azithromycin, Baclofen, Birth control pills, Bismuth subsalicylate, Buprenorphine-naloxone, Calcium carbonate, Cannabis, Carvedilol, Celecoxib, Cephalexin, Cetirizine, Ciprofloxacin, Clindamycin, Clonazepam, Clonidine, Clopidogrel, Codeine, Colchicine, Creatine, Diazepam, Diclofenac, Digoxin, Diphenhydramine, Doxycycline, Doxylamine, Empagliflozin, Esomeprazole, Estradiol, Famotidine, Fexofenadine, Finasteride, Fish oil, Fluconazole, Furosemide, Gabapentin, Glipizide, Grapefruit juice, Guaifenesin, Hydrochlorothiazide, Hydrocodone, Hydroxychloroquine, Hydroxyzine, Ibuprofen, Insulin, Iron supplements, Isotretinoin, Kratom, Lamotrigine, Levetiracetam, Levofloxacin, Levothyroxine, Lisinopril, Loperamide, Loratadine, Lorazepam, Losartan, Magnesium, Meclizine, Melatonin, Meloxicam, Metformin, Methocarbamol, Methotrexate, Methylprednisolone, Metoprolol, Metronidazole, Montelukast, Morphine, Naltrexone, Naproxen, Nicotine, Nitrofurantoin, Omeprazole, Oseltamivir, Oxycodone, Pantoprazole, Paxlovid, Potassium supplements, Pravastatin, Prednisone, Pregabalin, Probiotics, Promethazine, Propranolol, Quetiapine, Rivaroxaban, Rosuvastatin, Semaglutide, Sildenafil, Simvastatin, Spironolactone, Sulfamethoxazole-trimethoprim, Tadalafil, Tamsulosin, Tirzepatide, Tizanidine, Topiramate, Turmeric, Valacyclovir, Vitamin D, Warfarin, Zinc, Zolpidem.
Add at least two medicines, supplements or alcohol.
Sources
Source: FDA label for Amphetamine salts on DailyMed (effective 2026-08), plus the labels of each interacting medicine.
This list covers the 147 medicines and substances in our database. It is not a complete list of every possible interaction. Always tell your doctor and pharmacist about every medicine, supplement and herbal product you take.